The BioConnected HR+ headphones have a very standard, vocally driven pairing mechanism that should prove no issue if you've paired any Bluetooth devices in the past. If you do want to use BioConnected's app, you'll have to download it beforehand and sign up for a free profile.
Fitness headphones historically haven't offered the best of premium audio, and the BioConnected HR+ are very much fitness headphones. You can guess what's coming, right? They're entirely adequate headphones for working out to, but they're not high end in terms of their overall audio output, with somewhat weak bass notable across multiple tracks.
While I was out running and groaning, that didn't matter so much, but when I was sitting quietly listening, it was more apparent to me. Again, this is absolutely par for the course when it comes to fitness headphones. They're not noise cancelling headphones, but the combination of bud and shark fin does give them a fair degree of noise isolation if you like blocking the world out while you work out.

I did have the noted issue with wearing them while sitting at my desk and getting uncomfortable. But while out running their general light weight and a few neat inclusions such as the volume control sloping backwards down my neck did make them more comfortable than some headphones I've used while running.
Speaking of movement, the one significant Bluetooth limitation I hit with the HR+ headphones was Bluetooth range. When you're running with your phone in an armband or in your hand it's no issue, but beyond just a few metres from my phone, the audio from the HR+ headphones got noticeably sketchy. Again, this speaks to their core focus as a set of running headphones, but if you do like to wander with your headphones on, it's a concern.
Battery life is moderate given their size, although I did hit one unusual bug during my testing. At one point the headphones went flat without warning, at which point the app stopped working. I can very much understand that without power they couldn't pump audio to my ears or data about my blood flow to the app, but they're already relying on GPS tracking within the phone for speed data. It would have been nice to be able to finish my run and at least get some comparative data for it.